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Female or male age-matched mice (712 weeks old) were used for all experiments (unless otherwise stated) and euthanasia was performed by cervical dislocation

This paper describes the first structure of a GPCRG-protein complex, highlighting receptor-mediated conformational changes within the G protein that are important for nucleotide release

7.5 mg of tirzepatide equals 75 units at a concentration of 10 mg/mL, or 50 units at a concentration of 15 mg/mL
