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Since the first isolation and discovery of histone acetylation in 1964, 14 various forms of histone modifications, including such as methylation, phosphorylation, and ubiquitination have been gradually revealed (Fig

S., Abassou, H

Ecotoxicol Environ Saf 69:180186 Uno S, Nebert DW, Makishima M (2018) Cytochrome P450 1A1 (CYP1A1) protects against nonalcoholic fatty liver disease caused by Western diet containing benzo [a] pyrene in mice

The IRIS 203 trial showed that pioglitazone reduced the incidence of any stroke in nondiabetic patients with IR and stroke, suggesting that pioglitazone has glucose-independent cardiovascular benefits

demonstrated reduced mitochondrial ATP production rate (MAPR) in organelles extracted from diaphragm of mdx mice (21)