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2017 Jul 20;8:333
Sublingual administration Sublingual delivery places the peptide solution under the tongue, allowing absorption through the oral mucosa
The 26kDa GST affinity tag enhances the solubility of many eukaryotic proteins expressed in bacteria
The maximum plasma concentrations (C(max)) of adducts for immediate release (IR) and extended release (ER) formulations were 0.108 (0.020) and 0.100 (0.028) nmol/mL serum, respectively, and were two orders of magnitude lower than the maximum APAP adduct levels previously reported in adults with acute liver failure secondary to APAP
