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Both of these cells require glucose as an energy source, leading to a competition between them for glucose uptake in the TME [59,60,61]

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Unlike earlier GHRPs such as GHRP-6 or GHRP-2, Ipamorelin demonstrates a favorable selectivity profile in research models stimulating GH release while showing minimal interaction with cortisol, prolactin, or ACTH secretion pathways in controlled settings