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Regulation of mitochondrial processes by protein S-nitrosylation

During the transition from stage I to stage II, PMEL fibrils form and assemble laterally into sheets, a process essential for the structural organization of melanosomes

On MR imaging (MRI), Type 1 predominant tumors tend to be small and homogeneous while heterogeneous tumors (with or without cystic degeneration) tend to have higher proportions of Type 2

Hyperpigmentation effects are dose-cumulative and persist 816 weeks after protocol completion as melanin-containing keratinocytes migrate through the epidermis during normal skin turnover