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Wong et al., 2021)
Additionally, inhibiting Gln metabolism can reverse chemotherapy resistance
In this study, we have revealed the importance of the glutamate-generating metabolism, as shown by a complete depletion of glutamine (Gln) in the medium during H
It was observed that CD133 + HCC cells display a notable resistance to cisplatin compared to CD133- HCC cells
The universal role of NADPH as the primary electron donor for most biological reductions, including for supporting disulfide reduction systems, made the uncovering of an apparently NADPH-independent disulfide reduction system in mouse liver surprising
