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Description
SLC33A1 exports oxidized glutathione to maintain endoplasmic reticulum redox homeostasis

Chronic central neuropathic pain may be spontaneous or evoked, like hyperalgesia (exaggerated pain response) or allodynia (pain from normally non-painful stimuli)

doi: 10.1080/17425247.2019.1598375

Future research should focus on improving SAMe delivery, identifying biomarkers for patient-specific treatments and integrating SAMe with existing therapies

inhibiting HIF-1-mediated glycolysis mitigates chondrocyte ferroptosis and slows OA progression (Li et al., 2025b