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Expected 12-week outcome without AOD-9604: approximately 5-6 kg total weight loss, roughly 3.5-4 kg from fat, 1-2 kg from lean tissue and water
On the contrary, arabinose-derivatives are covalent inhibitors of CD38, and their potency is further increased when the 2-hydroxyl group was replaced by a fluoride (Table 2 and Figure 4)
Ewing, B., Hillier, L., Wendl, M
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Equally, Pfmdr1 gene amplification was not discerned in any of the study samples
