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The normal slow loss of cellular GSH from cultured astrocytes [30, 33] was found accelerated in a time- and concentration-dependent manner by the presence of either DI or OI

However, the ability of IGF-1 to stimulate proteoglycan synthesis in chondrocyte decreases with the age of the donor increasing [39]

Probing mono- and di-methylated arginine in the same cells showed somewhat less pronounced methylation inhibition, which was also rescued by WT MTAN (Supplementary Fig

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