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Each of these appears to have the potential to act as an effective nootropic given the current evidence

Clinical safety and efficacy of allogenic human adipose mesenchymal stromal cells-derived exosomes in patients with mild to moderate alzheimer's disease: a phase I/II clinical trial

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Just like cellular localization tags, degron tags are present in many natural proteins, and can also be rewired so that scientists can modify the abundance of a protein in cells or even entire organisms (Hernndez-Morn et al, 2024)