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This leads to impaired ubiquitination of NRF2, an increase of NRF2 protein levels [157], and a reduction of KEAP1 levels able to sequester de novo synthesized NRF2 [159]

Basic dosage: 2.5-3.75 micrograms/kilogram of body weight/time/twice a day

The combination targets different aspects of the problem

Another study exploring the association between folate and symptoms of schizophrenia indicated that low folate was associated with negative symptoms severity in schizophrenia subjects 94
