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introduction of two random mutations of Y444A and G484A to D433N resulted in up to 50-fold increase in catalytic efficiency for GL-7-ACA substrate (Yamada et al., 2008)

The advantage of this type of compounds, apart from the reduction in side effects, is their efficient metabolism to non-toxic products and a high affinity for specific molecular targets, which can potentially be associated with enhanced treatment efficacy, enabling the use of a relatively low dose to produce identical biological effects [3]

10.1177/0960327118792051 Summary Keywords environmental toxins, cadmium, arsenic, pesticides, cardiotoxicity, natural products Citation Yang Y, Wei S, Zhang B and Li W (2021) Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products

Family conflict, autonomic nervous system functioning and child adaptation: state of the science and future directions