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Chronic oral toxicology studies in Han Wistar rats (6 months) and cynomolgus monkeys (9 months) found no treatment-related unscheduled deaths, toxicologically significant clinical signs, or adverse changes in organ masses, electrocardiographic parameters, or histological profiles at the concentrations examined

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BPC-157 has also been found to interact with the nitric oxide system, providing endothelium protection and an angiogenic effect

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