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(2017) 12:e0180464

Both AgNPs and Ag + ions can alter the three-dimensional structure of proteins, disrupt disulfide bonds, and block active binding sites, ultimately impairing bacterial proliferation and contribute to AgNP-mediated cytotoxicity (Lok et al., 2006)
doi:10.1016/j.jnutbio.2005.05.013
In sick dogs, oxidative stress can increase, and glutathione is one of the key internal compounds involved in reducing that load
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