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Liver steatosis is caused by these gene mutations [9]
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The ability of these allelic variants to catalyze the GSH conjugation of reactive metabolites of acetaminophen, clozapine and diclofenac formed by bioactivation in in vitro incubations by human liver microsomes and drug-metabolizing P450 BM3 mutants has been studied [34]
Biofactors 15:123125
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