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Source : Watanabe F., et al

Neoplasia 10 , 329340 (2008)

16 Ivacaftor stabilizes the open state of CFTR, thus increasing chloride transport of wild-type CFTR and stimulates the activity of G551D-CFTR to 50% of that of non-mutated CFTR

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Ascorbic acid is another potentially valuable compound that may protect both glutathione and the glutathione-like regions of opioid and adrenergic receptors [122]