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Description
CRH-R2, as noted above, binds the urocortins 1, 2 and 3, and appears to mediate a down-regulatory role in the HPA response to stress: knockout mice exhibit a hypersensitive acute ACTH and corticosterone response (198) and a defective recovery from stress with a slower drop in corticosterone (199)
Its action is potent but less selective
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Femiano F., Scully C
After 10 days colonies were stained with a 0.4% methylene blue (Sigma-Aldrich) in 70% ethanol solution
