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Their findings indicated that NAC (1000 mg/kg, intraperitoneally) effectively countered GSH depletion caused by 2-cyclohexene-1-one in both saline and amphetamine-treated rats

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PKUMDL-LC-101 and its optimized analog PKUMDL-LC-101-D04 were the most effective in boosting GPX4 activity, though their IC50 values are above 100 M, making them moderate ferroptosis inhibitors

[14] A GCL est localizada exclusivamente nos plastos, e a glutatin sintetase aparece tanto en plastos coma no citosol, polo que o GSH e a gamma-glutamilcistena son exportados desde os plastos ao citosol