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Chitosan/metal hybrid NPs synthesized via ionotropic gelation exhibited combined antibacterial and tissue regenerative capabilities, suggesting translational promise [156]

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However, factors such as stress, poor nutrition, and environmental toxins can disrupt this delicate equilibrium, leading to oxidative stressa condition characterized by an excess of free radicals that can damage cells

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Interestingly, Dicer1 was found to be inducible by hypoxia and to be necessary for the function of HIFs and full expression of HIF target genes [149] from which some are eventually -catenin repressors