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Other studies examining blood serum and plasma GSH concentrations have also identified significantly lower GSH in MDD patients compared with healthy patients (33, 35)

Worsening intracellular oxidative potential was accompanied by increases in intracellular expression of downstream T2 signature proteins, such as POSTN and CCL26, with nonsignificant increases in inducible NO synthase (iNOS/NOS2

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HMGB1, a nonhistone nuclear protein abundant in mammalian chromatin, is involved in DNA transcription, repair, replication, and remodeling (Liu et al., 2010)

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