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Funding: These studies were sponsored by Sigma-Tau SpA

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A proposed molecular mechanism of MSG-induced ROS production is that chronic MSG exposure increases the production of Glutamate which may raise the activity of one of the potential ROS generators like -ketoglutarate dehydrogenase in the rat kidney

Sin embargo, debido a que el trabajo de seleccin de cepas es bastante complejo y los niveles de fermentacin an son relativamente bajos, muchas investigaciones siguen limitndose al nivel de laboratorio

acetylation, methylation or glycosylation), transduce the information on the cell metabolic status, and modulate the activities of signaling proteins, enzymes, and transcriptional regulators 3