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many of these transporters are Na + -dependent, and hence, the astrocytic 2-containing Na + K + pump is central for astrocytes homeostatic capacity 20

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Interestingly, the analysis also noted an increased fracture risk in men with overweight and obesity after adjusting for bone density

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If ETC function is impaired, the TCA cycle can continue to generate metabolites by reductive mechanisms, including using pyruvate carboxylase to generate oxaloacetate from pyruvate for aspartate production, and glutamine-dependent reductive carboxylation for citrate synthesis (22, 23)