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Several studies show that IGF-1 is closely related to the metabolism of cancer[16-19]

Clinical studies support this: exposure to diesel exhaust particles (DEPs) reduces peroxisomal ACOX1 expression in bronchial epithelial cells from asthma patients (105), exacerbating PUFA accumulation and ferroptosis

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A possible cascade which is caused by the release of nutrients in the aquatic ecosystems is shown in Figure 8