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doi: 10.1016/b978-0-12-385855-9.00005-9
It binds within the ERR ligand-binding domain and enhances transcriptional activity at ERR response elements, recruiting coactivators such as PGC-1/
5, May 2017, pp
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Preclinical data suggest that dual blockade of IL-4R and PD-1 leads to a more permissive immune landscape, characterized by reduced macrophage-mediated immune suppression and enhanced T cell infiltration
