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10.1016/j.talanta.2020.120909 4 BalkouraniG.BrouzgouA.ArchontiM.PapandrianosN.SongS.TsiakarasP

Clin Chimica Acta (2006) 365(1-2):297303

Funding The study was supported by a Start-Up Grant from University Grants Commission (UGC) Grant No

Even TfR, the most widely and successfully investigated target for receptor-mediated brain drug delivery, is present throughout the body [8, 19, 20]

The decrease in GSH disrupted the REDOX balance, preventing the consumption of intracellular ROS and lipid peroxides, and contributing to oxidative stress in cells, manifesting as a decrease in antioxidant proteins and the appearance of DNA damage