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MET remains active and triggers activation of ERK1/2, STAT3 and Rac1 from within endosomes [3,4,5], as opposed to the classical view of RTK signalling from the plasma membrane only (Fig

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These modifications result from direct ROS attack on amino acids (proline, arginine, lysine, threonine) or indirectly via reactive aldehydes from lipid peroxidation (MDA, 4-hydroxynonenal), or through reactions with reducing sugars and advanced glycation end-products (Pinzaru et al., 2023)

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Ingredients like vitamin C and retinoids are particularly effective in treating sun-induced pigmentation

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It may only be accessed through research channels

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Indication: As an adjunct treatment to minimize the occurrence of toxicity associated with cisplatin chemotherapy

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