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doi: 10.4103/1995-7645.291036

In patients with treatment-resistant depression, naltrexone 50 mg blocked the antidepressant but not the dissociative effects of KET, suggesting that the opioid system may also be required for KET antidepressant activities (Williams et al., 2018)

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Important digression for context What becomes critical to understand for our subsequent discussions is that the apoB particles have the potential to deliver cholesterol into an artery wall (the problem were trying to avoid), and 90-95% of the apoB particles are LDL particles