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2025;118 doi: 10.1016/j.ebiom.2025.105836

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Notably, normal rats exhibited a portal pressure of 35 mmHg[25] similar to that of the inferior vena cava, though with at least 1 mmHg higher values in the portal vein

Theoretical concerns regarding TB-500's effects on cell migration and potential implications for existing malignancies apply to the combination as well

The distinction between Drug Substance (DS), Drug Product (DP), and method-of-use (U-68) patent flags determines how costly and time-consuming a generic challenge will be, directly affecting the risk-adjusted NPV of any ANDA program