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Diabetes causes an early reduction in autonomic ganglion blood flow in rats

2.4 Methodological Quality Appraisal To investigate the methodological quality of the evaluated studies, we used the Cochrane risk of bias tool for randomized trials (version 2, RoB 2, London, United Kingdom), which consists of six main items for evaluating study quality: the randomization process, intervention adherence, missing outcome data, outcome measurement, selective reporting, and the overall risk of bias (Sterne et al., 2019)

Beyond the aforementioned biological activities, turmeric has been used in traditional medicine and contemporary and alternative medicine to manage conditions like anemia, indigestion, diabetes, hemorrhoids, edema, hepatitis, atherosclerosis, hysteria, wound healing, urinary diseases, psoriasis, rheumatism, anorexia, dermal diseases, inflammation, hepatic disorders, cough, and sinusitis (51, 52)

DISCUSSION In an attempt to elucidate the sudden onset of encephalopathy with paracetamol overdose (3), this study established a consistent BPC 157 beneficial effect in paracetamol-rats, given in early or advanced stage of paracetamol toxicity