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Furthermore, by using BSO a chemical inhibitor of glutamate cysteine ligase (GCL), an enzyme responsible for glutathione synthesis we depleted glutathione levels in A549 cells and observed significant increase in sensitivity to cisplatin, confirming the importance of glutathione in determining cisplatin resistance
doi: 10.3390/ijms20030765
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Capsaicin improves systemic inflammation, atherosclerosis, and macrophage-derived foam cells by stimulating PPAR gamma and TRPV1 receptors
doi: 10.1007/s10930020-099358 50 TonelliC.ChioI
