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The field requires urgent Phase I/II human trials before any clinical recommendations can be made

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GLP-1 Based Stacks: Semaglutide or Tirzepatide + Complementary Peptides Semaglutide and tirzepatide produce dramatic weight loss (15-22% body weight over 72 weeks per the SURMOUNT trials) (Jastreboff et al., NEJM, 2022)

Curr Clin Microbiol Rep