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Glucose-6-phosphate dehydrogenase deficiency and risk of diabetes: a systematic review and meta-analysis

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IGF-1 is produced throughout ones lifespan, typically peaking around puberty (6)

Furthermore, while AML blasts generally exhibit high glycolytic capacity, the more immature CD34 + CD38 low/ LSC compartment shows a significantly increased mitochondrial dependence and reduced glycolytic capacity compared to the bulk CD34 + population, particularly in intermediate- and adverse-risk patients [121]