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Alzheimers Disease International, London
To control the genes to start or stop being expressed, we need a regulatory system
Nat Chem Biol 18(1):91100 Kalkavan H et al (2022) Sublethal cytochrome c release generates drug-tolerant persister cells

[DOI] [PubMed] [Google Scholar] 258

There is no standardized design to determine MTD based on the occurrence of DLTs but all include a stepwise increase in dose.54 As described above, dose escalation can occur within a subject or dosing by cohort