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At the molecular level, AHK-Cu also increases VEGF (vascular endothelial growth factor) production to improve scalp blood flow, and upregulates SOD (superoxide dismutase) to reduce the oxidative stress that triggers DHT-driven follicle miniaturization one of the primary mechanisms behind androgenetic alopecia

The Chief Naturopathic medical officer of the Canadian College of Naturopathic Medicine wrote in 2011 serum levels of B12 not classically deficient by current laboratory standards are associated with neuropsychiatric signs and symptoms and Most clinicians do not consider vitamin B12 important unless the serum level is deficient when indicated by laboratory reference ranges

It's relatively straightforward to treat but, left unchecked, may result in low mood, anxiety, and cognitive issues

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While not approved for human or veterinary use, AHK-Cu continues to generate strong interest as a research compound across cellular and tissue model studies