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Alpha GPC easily crosses the blood-brain barrier and is rapidly absorbed by brain tissue, increasing plasma and brain choline levels

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Dogs receiving high-calorie intake (120% MER) exhibited a dose-dependent reduction in feed consumption and significant body weight decrease at doses of 236 mg and 492 mg of L-carnitine, independent of exercise, and this was mostly found in females

These data suggest that there are similar pathological processes between a subset of ASD children and an animal model of ASD with acquired mitochondrial dysfunction