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T2-P4 Severe Hemolysis on the First Dose of an 8-Week Primaquine Regimen for Radical Cure of Plasmodium vivax Infection in a Child with Severe G6PD Deficiency Erni J Nelwan 1 , Inge Sutanto 2 , Sherley Angeline 3 , Zaitunnah 4 , Illene Nanine 5 , Ric N Price 6 , Ari W Satyagraha 7 1 Division of Tropical Medicine and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia

Acta Otolaryngol

10 GCL is composed of two subunits: a heavy, catalytic subunit (GCLC) and a light, modifier subunit

2.10.1 Limitation of in-vitro model Despite their value in mechanistic research, in vitro models present several critical limitations that constrain their translational applicability (Blanchard et al., 2022)