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Syringic acid protective role: combatting oxidative stress induced by uvb radiation in l-929 fibroblasts
We have shown that effective pharmacologic inhibition of GPX4 in PTC cells with direct inhibitor RSL3 induces a robust activation of ferroptosis, increased DNA damage, impaired DNA damage repair response due to reduced p-NPM1 levels, decreased cell viability and cell migration, as well as suppressed spheroid formation and viability in vitro
10.1152/physrev.00026.2013 Summary Keywords bridging factors, autophagy, Nrf2-Keap1, TRIM16, SQSTM1, Sestrin2 Citation Ning B, Hang S, Zhang W, Mao C and Li D (2023) An update on the bridging factors connecting autophagy and Nrf2 antioxidant pathway
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Free Radic Res Commun
