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Controlled walking patterns were done with cameras set sideways positioned at 12 cm from the running walkway

In control animals, the damaged trauma area gets slightly increased until day 3 post TBI, thereafter, remodeling of the tissue damage was steadily progressing, leading to a marked reduction in the overall lesion size at day 15 post TBI

While 503B outsourcing facilities are subject to federal Current Good Manufacturing Practice (CGMP) regulations and must register with the FDA, traditional 503A compounders are exempt from CGMP regulations and are instead overseen primarily by state boards of pharmacy, potentially resulting in a patchwork of manufacturing regulation and oversight across states (Lisi, 2021

Funding This work was supported by the Deutsche Forschungsgemeinschaft (DFG) SFB-TR 338 (LETSimmun)project number: 452881907, SFB 1526 (PANTAU), project number: 454193335

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