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Pulmonary artery endothelial cells (PAECs) and lung tissues from monocrotaline (MCT)-induced PH rats were analysed for ferroptosis markers, including lipid peroxidation, the labile iron pool (LIP) and the protein expression of glutathione peroxidase 4 (GPX4), ferritin heavy chain 1 (FTH1) and NADPH oxidase-4 (NOX4)
Posted byAnne Hermannon Wed, Apr 04, 2012 @ 12:46 PM Anne Hermann, MD WhyMIC B
Glutathione (GSH) is the most abundant non-protein thiol present at millimolar concentrations in mammalian tissues
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