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The combination group had a significantly lower 10-year atherosclerosis and cardiovascular disease risk (a multicomponent measure of risk of a cardiac event within a 10-year window) at the end of the study compared with the statin-only group

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By days 4 and 5, nhr-49(nr2041) animals were significantly smaller than WT, vacuoles were ubiquitous, and there was widespread gonadal necrosis

doi: 10.1186/1477-7827-3-28

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