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In a clinical sample of 116 participants [30], subjects with Major Depressive Disorder (MDD) showed significantly lower C2 levels than healthy controls

Currently, two main theories are widely accepted, including the trigeminovascular system (TGVS) theory and the cortical spreading depression (CSD) theory
Mayford et al, 1996) was used to assess spatial learning and memory through training a mouse to seek and enter a target hole

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It plays a crucial role in cellular energy metabolism by facilitating -oxidation, the process by which fatty acids are converted into energy