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ISR has been evaluated as an essential element to UPR mt activation via selective translation of transcription factors, such as ATF4, ATF5 and DNA-damage-inducible transcript 3 (CHOP), and attenuation of global protein synthesis by activation of eukaryotic translation initiation factor 2 (eIF2) complex subunit 2 (eIF2

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PPAR-gamma is a major driver of the accumulation and phenotype of adipose tissue Treg cells

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