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Description
In the case of producing your bodys primary methyl donor, SAMe you need homocysteine

doi: 10.1038/s41568-019-0235-4 50 WuTDMadireddiSde AlmeidaPEBanchereauRChenYJJChitreASet al
Most common: Acne / oily skin Libido changes Mood fluctuations (including irritability) Fluid retention Injection site pain, swelling, or bruising Elevated blood pressure Elevated hematocrit, hemoglobin, and PSA (lab monitoring required) Testicular shrinkage / atrophy Gynecomastia Night sweats Serious side effects may include: Polycythemia / elevated hematocrit (monitor CBC) Suppression of spermatogenesis / infertility while on treatment Elevated PSA Sleep apnea exacerbation DVT or PE (rare

Studies on its potential toxicity indicated that it is generally safe, even at larger quantities (up to 12 g in human)
France 2007 - Recipient of NIH/NIGMS MERIT Award
