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For example, THC (3 mg/kg, i.p) administered to WT mice resulted in reduced RhoA/ROCK proteins compared to vehicle exposed mice, leading to increased myelin-related proteins and enhanced OPC differentiation (Snchez-de la Torre et al., 2022)

Luciferase activity assay was carried out using the Dual-Luciferase TM Assay System (Promega) and the transfection efficiency was normalized using a cotransfected renilla plasmid ( Construction of OXT/OXTR Reporter Plasmid Human genomic DNA was prepared from NPC cells

By exploiting the mediating effects of these receptors, nanocarriers can facilitate trans-BBB drug delivery, thereby providing novel therapeutic approaches for CNS diseases

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