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Description
"Off-Target drug effects resulting in altered gene expression events with epigenetic and "Quasi-Epigenetic" origins"
PBMC , peripheral blood mononuclear cells
So, remember, more isn't always better
Despite promising preclinical studies, MMP inhibitors failed in phase III clinical trials for cancer, which was mainly attributed to their severe side effects, lack of target specificity, and inadequate knowledge of MMP functions in diseases (72, 73)
Encourages angiogenesis , aiding tissue repair at injury sites
