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doi: 10.1155/2019/7547382.7547382 [DOI] [PMC free article] [PubMed] [Google Scholar] 114.Hara Y

In patients with mild-to-moderate acute lung injury, intravenous (IV) NAC treatment (40mg/kg/day) for 3 days significantly improved systemic oxygenation, reduced the need for ventilatory support and also slightly reduced the mortality rate,41 suggesting that higher concentrations of IV NAC could be administrated, potentially improving clinical outcomes

166,190 Further, in gastrointestinal cancer cells, genetic inhibition or pharmacological treatment of CPT2 with perhexiline disrupts NADPH and promotes cell apoptosis after oxaliplatin treatment