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This can occur due to conditions such as pernicious anemia, gastrointestinal disorders like Crohns disease, or following gastrointestinal surgery
It maintains effectiveness over extended use

This route achieves higher bioavailability than oral supplements, making it effective for patients with absorption issues or documented deficiency
A diet that includes meat, fish, and dairy products can provide natural sources of B12

doi:10.1152/ajpendo.2000.279.3.E501 Ng FM, Sun J, Sharma L, Libinaka R, Jiang WJ, Gianello R
