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LCACs also perturb Ca 2+ homeostasis in the cytoplasm and have been shown to disrupt myocardial contractility and electrophysiology, thereby inducing cardiomyopathy and arrhythmias [294]

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Manufactured under controlled conditions, it is prepared to support reliable use within research environments

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The guides address issues that are specific to particular drugs and drug classes, and they contain FDA-approved information that can help patients use the medicine safe and effectively and try to avoid serious adverse events