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the multifunctional growth factor hepatocyte growth factor (HGF) and its receptor Met are important mediators for mitogenesis, motogenesis, and morphogenesis in a wide range of cell types including epithelial, endothelial, and hematopoietic cells, neurons, melanocytes, and hepatocytes

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Most interestingly, ageing reduces NMDA-receptor-dependent LTP across the spectrum of cognitive outcomes, whereas increased NMDA-receptor-independent LTP occurs exclusively in high-performing aged rats indicating that a shift to NMDA-receptor-independent pathways for neural plasticity is an adaptive mechanism with better cognitive outcomes in ageing (Figure 1)

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15 Pre- and post-operative nutrition optimization support enhanced musculoskeletal recovery and long-term bone health