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PKB/Akt phosphorylates and activates phosphodiesterase 3B, which degrades cAMP in adipocytes, releasing PKA from activation and decreasing lipolysis through a reduction in the phosphorylation-mediated activation of HSL and perilipin

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J Lab Clin Med 144(1):3137 Lee CH, Park JH, Yoo K-Y, Choi JH, Hwang IK, Ryu PD, Kim D-H, Kwon Y-G et al (2011) Pre-and post-treatments with escitalopram protect against experimental ischemic neuronal damage via regulation of BDNF expression and oxidative stress